The Megakaryocyte Potentiating Factor (MPF) Antibody from MyBioSource.com is a Human, and Mouse Monoclonal antibody to Mesothelin, MPF, and Msln. This antibody recognizes Human antigen. The Megakaryocyte Potentiating Factor (MPF) Antibody has been validated for the following applications: ELISA, and Western Blot.
Description
Megakaryocyte Potentiating Factor (MPF) is a 33kD soluble protein that is cleaved as an N-terminal propeptide from the mouse mesothelin preproprotein by furin, while the C-terminal portion is processed further to form mesothelin. Mouse MPF potentiates megakaryocyte colony forming activity of IL-3 in mouse bone marrow culture. Human MPF shows 55% amino acid identity with mouse or rat MPF. The preproprotein is produced by mesothelial cells and is also highly expressed in pancreatic, gastric and ovarian carcinomas